Mass Spectrometric Analysis of Histone Proteoforms
نویسندگان
چکیده
منابع مشابه
Mass Spectrometric Immunoassays in Characterization of Clinically Significant Proteoforms
Proteins can exist as multiple proteoforms in vivo, as a result of alternative splicing and single-nucleotide polymorphisms (SNPs), as well as posttranslational processing. To address their clinical significance in a context of diagnostic information, proteoforms require a more in-depth analysis. Mass spectrometric immunoassays (MSIA) have been devised for studying structural diversity in human...
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ژورنال
عنوان ژورنال: Annual Review of Analytical Chemistry
سال: 2014
ISSN: 1936-1327,1936-1335
DOI: 10.1146/annurev-anchem-071213-015959